发表文章

Lei Chen*, Zhi-Hao Jiao*,Li-Sha Zheng*(共同第一作者),Yuan-Yuan Zhang, Shu-Tao Xie, Zhi-Xin Wang & Jia-Wei Wu. Structural insight into the autoinhibition mechanism of AMP-activated protein kinase.Nature2009;459(7250): 1146-9

Zheng, L., Chen, L., Chen, Y., Gui, J., Li, Q., Huang, Y., Liu, M., Jia, X., Song, W., Ji, J., Gong, X., Shi, R., Fan, Y., The effects of fluid shear stress on proliferation and osteogenesis of human periodontal ligament cells.J Biomech. 2016. Feb 6. pii: S0021-9290(16)30064-1. doi: 10.1016/j.jbiomech.2016.01.034.

Luoping Chen,Lisha Zheng*(共同通讯), Jingyi Jiang, Jinpeng Gui, Lingyu Zhang, Yan Huang, Xiaofang Chen, Jing Ji, Yubo Fan*.Calcium Hydroxide Induced Proliferation, Migration, Osteogenic Differentiation and Mineralization via MAP kinase Pathway in Human Dental Pulp Stem Cells.Journal of Endodontics(Accepted)

Zheng LS, Liu YT, Chen L, Wang Y, Rui YN, Huang HZ, Lin SY, Wang J, Wang ZX, Lin SC, Wu JW. Structure and mechanism of the unique C2 domain of Aida.FEBS J. 2014 Oct;281(20):4622-32. doi: 10.1111/febs.12966. Epub 2014 Sep 6.

Zheng L, Huang Y, Song W, Gong X, Liu M, Jia X, Zhou G, Chen L, Li A, Fan Y. Fluid shear stress regulates metalloproteinase-1 and 2 in human periodontal ligament cells: involvement of extracellular signal-regulated kinase (ERK) and P38 signaling pathways.J Biomech. 2012 Sep 21;45(14):2368-75. doi: 10.1016/j.jbiomech.2012.07.013. Epub 2012 Aug 3.

Zheng LS, Zhang YY, Wu JW, Wu Z, Zhang ZY, Wang ZX.A continuous spectrophotometric assay for mitogen-activated protein kinase kinases.Anal Biochem. 2012 Feb 1; 421(1):191-7. Epub 2011 Dec 1.

Huang Y,Zheng L, Gong X, Jia X, Song W, Liu M, Fan Y. Effect of cyclic strain on cardiomyogenic differentiation of rat bone marrow derived mesenchymal stem cells.PLoS One. 2012;7(4):e34960. doi: 10.1371/journal.pone.0034960. Epub 2012 Apr 4.

Huang Y, Zhou G,Zheng L, Liu H, Niu X, Fan Y. Micro-/nano- sized hydroxyapatite directs differentiation of rat bone marrow derived mesenchymal stem cells towards an osteoblast lineage.Nanoscale. 2012 Apr 7;4(7):2484-90. doi: 10.1039/c2nr12072k. Epub 2012 Feb 27.

Li X, Huang Y,Zheng L, Liu H, Niu X, Huang J, Zhao F, Fan Y. Effect of substrate stiffness on the functions of rat bone marrow and adipose tissue derived mesenchymal stem cells in vitro.J Biomed Mater Res A. 2014 Apr;102(4):1092-101. doi: 10.1002/jbm.a.34774. Epub 2013 Jun 11.

Wang L, Zhou G, Liu H, Niu X, Han J,Zheng L, Fan Y. Nano-hydroxyapatite particles induce apoptosis on MC3T3-E1 cells and tissue cells in SD rats.Nanoscale.2012 Apr 28;4(9):2894-9. doi: 10.1039/c2nr00044j. Epub 2012 Mar 27.

Gong X, Liu H, Ding X, Liu M, Li X,Zheng L, Jia X, Zhou G, Zou Y, Li J, Huang X, Fan Y. Physiological pulsatile flow culture conditions to generate functional endothelium on a sulfated silk fibroin nanofibrous scaffold.Biomaterials. 2014 Jun;35(17):4782-91. doi: 10.1016/j.biomaterials.2014.02.050. Epub 2014 Mar 15.

Liu M, Song W, Li P, Huang Y, Gong X, Zhou G, Jia X,Zheng L, Fan Y. Galanin protects against nerve injury after shear stress in primary cultured rat cortical neurons.PLoS One. 2013 May 14;8(5):e63473. doi: 10.1371/journal.pone.0063473. Print 2013.

Jia X, Yang J, Song W, Li P, Wang X, Guan C, Yang L, Huang Y, Gong X, Liu M,Zheng L, Fan Y. Involvement of large conductance Ca(2+)-activated K (+) channel in laminar shear stress-induced inhibition of vascular smooth muscle cell proliferation.Pflugers Arch. 2013 Feb;465(2):221-32. doi: 10.1007/s00424-012-1182-z. Epub 2012 Nov 21.

Huang Y, Deng H, Fan Y,Zheng L, Che J, Li X, Aifantis KE. Conductive nanostructured Si biomaterials enhance osteogeneration through electrical stimulation.Mater Sci Eng C Mater Biol Appl. 2019 Oct;103:109748. doi: 10.1016/j.msec.2019.109748. Epub 2019 May 17.

Zheng L, Shi Q, Na J, Liu N, Guo Y, Fan Y. Platelet-Derived Growth Factor Receptor-α and β are Involved in Fluid Shear Stress Regulated Cell Migration in Human Periodontal Ligament Cells.Cell Mol Bioeng. 2018 Aug 2;12(1):85-97. doi: 10.1007/s12195-018-0546-7.

Zheng L, Zhang L, Chen L, Jiang J, Zhou X, Wang M, Fan Y. Static magnetic field regulates proliferation, migration, differentiation, and YAP/TAZ activation of human dental pulp stem cells.J Tissue Eng Regen Med. 2018 Oct;12(10):2029-2040. doi: 10.1002/term.2737. Epub 2018 Sep 2. PMID: 30058115.

Zheng L, Jiang J, Gui J, Zhang L, Liu X, Sun Y, Fan Y. Influence of Micropatterning on Human Periodontal Ligament Cells' Behavior.Biophys J. 2018 Apr 24;114(8):1988-2000. doi: 10.1016/j.bpj.2018.02.041. PMID: 29694875; PMCID: PMC5937357.

Xie SA, Zhang T, Wang J, Zhao F, Zhang YP, Yao WJ, Hur SS, Yeh YT, Pang W,Zheng LS, Fan YB, Kong W, Wang X, Chiu JJ, Zhou J. Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo: Role of DNA methyltransferase 1.Biomaterials. 2018 Feb;155:203-216. doi: 10.1016/j.biomaterials.2017.11.033. Epub 2017 Nov 21.

Chen L,Zheng L, Jiang J, Gui J, Zhang L, Huang Y, Chen X, Ji J, Fan Y. Calcium Hydroxide-induced Proliferation, Migration, Osteogenic Differentiation, and Mineralization via the Mitogen-activated Protein Kinase Pathway in Human Dental Pulp Stem Cells.J Endod. 2016 Sep;42(9):1355-61. doi: 10.1016/j.joen.2016.04.025. Epub 2016 Jul 7.

Zheng L, Chen L, Chen Y, Gui J, Li Q, Huang Y, Liu M, Jia X, Song W, Ji J, Gong X, Shi R, Fan Y. The effects of fluid shear stress on proliferation and osteogenesis of human periodontal ligament cells.J Biomech. 2016 Feb 29;49(4):572-9. doi: 10.1016/j.jbiomech.2016.01.034. Epub 2016 Feb 6.

Zheng LS, Liu YT, Chen L, Wang Y, Rui YN, Huang HZ, Lin SY, Wang J, Wang ZX, Lin SC, Wu JW. Structure and mechanism of the unique C2 domain of Aida.FEBS J. 2014 Oct;281(20):4622-32. doi: 10.1111/febs.12966. Epub 2014 Sep 6.

Gong X, Liu H, Ding X, Liu M, Li X,Zheng L, Jia X, Zhou G, Zou Y, Li J, Huang X, Fan Y. Physiological pulsatile flow culture conditions to generate functional endothelium on a sulfated silk fibroin nanofibrous scaffold.Biomaterials. 2014 Jun;35(17):4782-91. doi: 10.1016/j.biomaterials.2014.02.050. Epub 2014 Mar 15.

Li X, Huang Y,Zheng L, Liu H, Niu X, Huang J, Zhao F, Fan Y. Effect of substrate stiffness on the functions of rat bone marrow and adipose tissue derived mesenchymal stem cells in vitro.J Biomed Mater Res A. 2014 Apr;102(4):1092-101. doi: 10.1002/jbm.a.34774. Epub 2013 Jun 11.

Zheng L, Huang Y, Song W, Gong X, Liu M, Jia X, Zhou G, Chen L, Li A, Fan Y. Fluid shear stress regulates metalloproteinase-1 and 2 in human periodontal ligament cells: involvement of extracellular signal-regulated kinase (ERK) and P38 signaling pathways.J Biomech. 2012 Sep 21;45(14):2368-75. doi: 10.1016/j.jbiomech.2012.07.013. Epub 2012 Aug 3.

陈罗萍,郑丽沙,樊瑜波.Wnt信号通路对氢氧化钙促进人牙髓干细胞成骨向分化的调控.国际生物医学工程杂志,2019,(02):120-124.

张灵玉,江静怡,樊瑜波,郑丽沙.磁场在骨生物学领域:研究与应用中明确和未明确问题.中国组织工程研究,2019,23(04):584-590.

张泽茜,伍佳琪,樊瑜波,郑丽沙.干细胞心肌向分化成熟过程中的物理刺激方法.中国组织工程研究,2019,23(01):110-117.

江静怡,樊瑜波,郑丽沙.力学因素对间充质干细胞神经向分化的影响.中国组织工程研究,2018,22(17):2761-2768.

陈罗萍,张桂荣,郑丽沙,黄燕,樊瑜波.流体剪切力对成骨细胞LEF-1蛋白表达的影响.现代生物医学进展,2013,13(22):4230-4232+4255.

周钢,孙艳,李萍,郑丽沙,宋崴,牛旭锋,刘文勇,刘美丽,樊瑜波,杨欣.生物医学工程专业微生物实验课程体系改革与实践.实验室研究与探索,2012,31(10):95-97+129.

黄天辉，桂金鹏，郑丽沙*，利用酶制剂改善再造烟叶品质研究进展，东北农业大学学报，2015，46(10): 102~108

陈雷，焦智浩，郑丽沙，张媛媛，解树涛，王志新，吴嘉炜.糖尿病关键蛋白AMPK的自抑制机制生物物理学报2009 25(Supp.): 97

郑丽沙，陈雷，王盈，王志新，王大成，林圣彩，吴嘉炜. Axin相关蛋白Aida的结构及功能研究第九届全国酶学学术讨论会暨邹承鲁诞辰85周年纪念会论文摘要集2008年